I found that Schwalbe 2.5" tires are about as large as the Maxxis Minion 2.7" tires, which were thoroughly out of fashion in recent years. But now with the advent of plus size tires, more people may give them a try.
The Schwalbe 2.5" tires share the problem with the 2.7" Maxxis tires though: weight. A 650B 2.5" Magic Mary weighs 1410 g (49 oz). A 2.35" is 1250 g, and the SuperGravity 2.35" version is only 1100 g. You definitely notice that difference in weight on the trail.
Also, I found that rolling resistance becomes noticeable on trails like A-Line when you follow a friend with faster rolling tires. Schwalbe makes three compounds. For the front, you definitely want the softest, VertStar. For durabilty and rolling resistance, you could consider the TrailStar for the rear tire. I believe it is still softer than Maxxis' MaxxPro, and it's a triple compound, so the side knobs should be a lot softer.
My first set of Schwalbe tires years back also had problems with knobs falling off, but I had no problems with newer ones. But because all their tires are either double or triple compound, they may still have a quality issue with the knobs tearing of where the compound changes. They will definitely warranty tires with ripped-off knobs. So -C-, if you kept yours, you may get brand new ones.