Here's some tips:
1) Around any div/object/element that is being manipulated by CSS: put a border around it make it red, this will help you align stuff as well as see where bounding boxes from other elements start and end.
2)Download Firebug: http://getfirebug.com/
3)Get the basic structure of the site up there, and then add the complex elements (pictures videos etc..)
Goodluck