Took one for a spin in the Spring (in the Soquel Demo Forest in Santa Cruz) - had a super fun ride. It bobbed a bit climbing, but felt super smooth on the descent. Usually I feel a bit out of sorts when I hop on a new bike, but I was comfortable on it right away.
I'm short (5'2") and previous version of the Slayer had minimal stand over clearance for me. The re-design this year gives me more room, and the bike over all felt less tall - for me it just fit really well. Previously the bike leaned more to the XC side of things and that's changed with the 06 model.
I haven't ridden either the Nomad or Enduro or another "all-mountain" (my main rig is a Knolly V-tach - which pedals smoother on the climb, but is much heavier!) to compare it to though sorry.
Boils down to where/what you're looking to ride, and fit…
Happy shopping,
pd